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Proteintech
MYCBP2 Polyclonal Antibody
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Product Details
27951-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MYCBP2 Fusion Protein Ag27228 (2672-2880 aa encoded by NM_015057)
Conjugate
Form
Liquid
Concentration
0.67 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MGNSKGDRG NISTSSKPAS TSGKSELSSK HSRSLKPDGR MSRTTADQKK PRGTESLSAS ESLILKSDAA KLRSDSHSRS LSPNHNTLQT LKSDGRMPSS SRAESPGPGS RLSSPKPKTL PANRSSPSGA SSPRSSSPHD KNLPQKSTAP VKTKLDPPRE RSKSDSYTLD PDTLRKKKMP LTEPLRGRST SPKPKSVPKD STDSPGSENR A (2672-2880 aa encoded by NM _015057)
Target Information
This gene encodes an E3 ubiquitin-protein ligase and member of the PHR (Phr1/MYCBP2, highwire and RPM-1) family of proteins. The encoded protein plays a role in axon guidance and synapse formation in the developing nervous system. In mammalian cells, this protein regulates the cAMP and mTOR signaling pathways, and may additionally regulate autophagy. Reduced expression of this gene has been observed in acute lymphoblastic leukemia patients and a mutation in this gene has been identified in patients with a rare inherited vision defect.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: E3 ubiquitin-protein ligase MYCBP2; Highwire; Myc-binding protein 2; pam/highwire/rpm-1 protein; probable E3 ubiquitin-protein ligase MYCBP2; Protein associated with Myc
Gene Aliases: KIAA0916; Myc-bp2; MYCBP2; PAM; Phr
UniProt ID: (Human) O75592
Entrez Gene ID: (Human) 23077
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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