Search

  • Contact Us
  • Quick Order

Bioss

MYCBP2 Polyclonal Antibody

View all (3) MYCBP2 antibodies

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

Datasheet
Certificates
Protocols
Questions & Answers
Tech Support
Datasheet
Certificates
Protocols
Questions & Answers
Tech Support
Datasheet
Certificates
Protocols
Questions & Answers
Tech Support
Additional Information:
{{banner.description}}
{{$ctrl.isSkuNotesCollapsed ? 'View more' : 'View less'}}
MYCBP2 Polyclonal Antibody

Product Details

BS-9375R

Applications
Tested Dilution
Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:400
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide derived from human MYCBP2, amino acids 60-100.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA

Contains

0.02% ProClin 300

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

This gene encodes an E3 ubiquitin-protein ligase and member of the PHR (Phr1/MYCBP2, highwire and RPM-1) family of proteins. The encoded protein plays a role in axon guidance and synapse formation in the developing nervous system. In mammalian cells, this protein regulates the cAMP and mTOR signaling pathways, and may additionally regulate autophagy. Reduced expression of this gene has been observed in acute lymphoblastic leukemia patients and a mutation in this gene has been identified in patients with a rare inherited vision defect.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?
Let us know so we can reference it here.
Cite this product

Bioinformatics

Protein Aliases: E3 ubiquitin-protein ligase MYCBP2; Highwire; MYC binding protein 2, E3 ubiquitin protein ligase; Myc-binding protein 2; mycbp2; pam, highwire, rpm 1; Pam/highwire/rpm-1 protein; PAM/Highwire/RPM-1 protein 1; PAM; nuclear; contains RCC1 repeats; probable E3 ubiquitin-protein ligase MYCBP2; Protein associated with Myc; Protein Magellan; RING-type E3 ubiquitin transferase MYCBP2; unnamed protein product

View more View less

Gene Aliases: AU023734; AW107953; AW546647; C130061D10Rik; KIAA0916; Myc-bp2; MYCBP2; PAM; Phr; PHR1; R75243

View more View less

UniProt ID: (Human) O75592, (Mouse) Q7TPH6

View more View less

Entrez Gene ID: (Human) 23077, (Rat) 290447, (Mouse) 105689

View more View less

Function(s)
guanyl-nucleotide exchange factor activity protein binding zinc ion binding transferase activity small GTPase binding identical protein binding metal ion binding ubiquitin protein ligase activity ubiquitin-protein transferase activity protein homodimerization activity UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity ligase activity ribosomal S6-glutamic acid ligase activity coenzyme F420-0 gamma-glutamyl ligase activity coenzyme F420-2 alpha-glutamyl ligase activity protein-glycine ligase activity protein-glycine ligase activity, initiating protein-glycine ligase activity, elongating tubulin-glycine ligase activity protein-glutamic acid ligase activity tubulin-glutamic acid ligase activity guanyl-nucleotide exchange factor ubiquitin-protein ligase protein modifying enzyme
Process(es)
axon guidance motor neuron axon guidance regulation of synaptic growth at neuromuscular junction protein ubiquitination branchiomotor neuron axon guidance central nervous system projection neuron axonogenesis positive regulation of protein ubiquitination regulation of protein localization circadian regulation of gene expression negative regulation of protein catabolic process rhythmic process cell morphogenesis involved in neuron differentiation neuromuscular process regulation of cytoskeleton organization axon development protein K48-linked ubiquitination regulation of axon guidance transcription, DNA-templated regulation of transcription, DNA-templated
guarantee_icon

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more
help_icon

We're here to help

Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

Contact tech support