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MYH Polyclonal Antibody
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Product Details
BS-15444R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human MYH 6.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Cardiac muscle myosin is a hexamer consisting of two heavy chain subunits, two light chain subunits, and two regulatory subunits. This gene encodes the alpha heavy chain subunit of cardiac myosin. The gene is located 4kb downstream of the gene encoding the beta heavy chain subunit of cardiac myosin. Mutations in this gene cause familial hypertrophic cardiomyopathy and atrial septal defect 3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alpha cardiac MHC; alpha myosin; alpha-myosin heavy chain; beta myosin heavy chain; beta-myosin heavy chain; cardiac muscle myosin heavy chain 7 beta; cardiac myosin heavy chain alpha isoform; cardiac myosin heavy chain beta isoform; cardiomyopathy, hypertrophic 1; MYH-beta/slow; MyHC-alpha; MyHC-beta; MyHC-slow; myosin 7; myosin heavy chain; Myosin heavy chain 6; Myosin heavy chain 7; myosin heavy chain beta-subunit; myosin heavy chain MYH7; muscle filament; myosin heavy chain polypeptide 6 cardiac muscle adult; myosin heavy chain polypeptide 7 cardiac muscle fetal; Myosin heavy chain slow isoform; Myosin heavy chain, cardiac muscle alpha isoform; Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha); Myosin heavy chain, cardiac muscle beta isoform; myosin heavy chain, cardiac muscle, adult; myosin heavy chain, cardiac muscle, fetal; myosin heavy chain, polypeptide 6, cardiac muscle, alpha; myosin heavy chain, polypeptide 7; myosin, heavy chain 7, cardiac muscle, beta; myosin, heavy polypeptide 6, cardiac muscle, alpha; myosin, heavy polypeptide 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1); myosin, heavy polypeptide 7, cardiac muscle, beta; Myosin-6; Myosin-7; rhabdomyosarcoma antigen MU-RMS-40.7A; sarcomeric protein; unnamed protein product
Gene Aliases: A830009F23Rik; AA517445; alpha-MHC; ASD3; B-MHC; beta-MHC; CMD1EE; CMD1S; CMH1; CMH14; CMYO7A; CMYO7B; CMYP7A; CMYP7B; MPD1; MYH6; MYH7; MYHC; Myhc-a; Myhc-b; MyHC-I; MYHCA; MYHCB; SPMD; SPMM; SSS3
UniProt ID: (Human) P13533, (Human) P12883, (Mouse) Q02566, (Mouse) Q91Z83, (Rat) P02564
Entrez Gene ID: (Human) 4624, (Human) 4625, (Mouse) 17888, (Rat) 29556, (Mouse) 140781, (Rat) 29557
microfilament motor activity
nucleotide binding
motor activity
actin binding
calmodulin binding
ATP binding
myosin phosphatase activity
protein kinase binding
actin filament binding
protein binding
ATPase activity
actin-dependent ATPase activity
calcium-dependent ATPase activity
identical protein binding
protein homodimerization activity
protein heterodimerization activity
non-receptor serine/threonine protein kinase
in utero embryonic development
regulation of the force of heart contraction
regulation of heart rate
muscle system process
muscle contraction
striated muscle contraction
adult heart development
visceral muscle development
regulation of heart contraction
regulation of blood pressure
cardiac muscle hypertrophy in response to stress
actin filament-based movement
muscle filament sliding
myofibril assembly
sarcomere organization
ATP metabolic process
atrial cardiac muscle tissue morphogenesis
ventricular cardiac muscle tissue morphogenesis
cardiac muscle cell development
cardiac muscle contraction
regulation of heart growth
skeletal muscle contraction
regulation of the force of skeletal muscle contraction
transition between fast and slow fiber
regulation of slow-twitch skeletal muscle fiber contraction
metabolic process
BMP signaling pathway
regulation of ATPase activity
cardiac muscle fiber development
canonical Wnt signaling pathway
response to heat
response to reactive oxygen species
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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