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Product Details
TA590547
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
DNA immunization. This antibody is specific for the C Terminus Region of the target protein.
Conjugate
Form
Liquid
Concentration
1.26 mg/mL
Purification
Protein A/G
Storage buffer
PBS
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Cardiac muscle myosin is a hexamer consisting of two heavy chain subunits, two light chain subunits, and two regulatory subunits. This gene encodes the alpha heavy chain subunit of cardiac myosin. The gene is located 4kb downstream of the gene encoding the beta heavy chain subunit of cardiac myosin. Mutations in this gene cause familial hypertrophic cardiomyopathy and atrial septal defect 3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cardiac muscle myosin heavy chain 7 beta; MyHC-alpha; MyHC-beta; MyHC-slow; myopathy, distal 1; Myosin heavy chain 6; Myosin heavy chain 7; Myosin heavy chain slow isoform; Myosin heavy chain, cardiac muscle alpha isoform; Myosin heavy chain, cardiac muscle beta isoform; myosin, heavy polypeptide 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1); myosin, heavy polypeptide 7, cardiac muscle, beta; Myosin-6; Myosin-7; rhabdomyosarcoma antigen MU-RMS-40.7A
Gene Aliases: alpha-MHC; ASD3; CMD1EE; CMD1S; CMH1; CMH14; MPD1; MYH6; MYH7; MYHC; MYHCA; MYHCB; SPMD; SPMM; SSS3
UniProt ID: (Human) P13533, (Human) P12883
Entrez Gene ID: (Human) 4624, (Human) 4625
microfilament motor activity
actin binding
calmodulin binding
ATP binding
ATPase activity
myosin phosphatase activity
protein kinase binding
actin-dependent ATPase activity
protein binding
protein homodimerization activity
protein heterodimerization activity
non-receptor serine/threonine protein kinase
in utero embryonic development
regulation of the force of heart contraction
regulation of heart rate
protein dephosphorylation
muscle contraction
striated muscle contraction
adult heart development
visceral muscle development
regulation of heart contraction
regulation of blood pressure
muscle filament sliding
myofibril assembly
BMP signaling pathway
regulation of ATPase activity
sarcomere organization
ATP metabolic process
cardiac muscle fiber development
atrial cardiac muscle tissue morphogenesis
ventricular cardiac muscle tissue morphogenesis
cardiac muscle contraction
canonical Wnt signaling pathway
regulation of heart growth
skeletal muscle contraction
regulation of the force of skeletal muscle contraction
transition between fast and slow fiber
regulation of slow-twitch skeletal muscle fiber contraction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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