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Proteintech
MYH10 Polyclonal Antibody, CoraLite® Plus 488
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Product Details
CL488-21403
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MYH10 fusion protein Ag16113
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: QEVAELKKA LEEETKNHEA QIQDMRQRHA TALEELSEQL EQAKRFKANL EKNKQGLETD NKELACEVKV LQQVKAESEH KRKKLDAQVQ ELHAKVSEGD RLRVELAEKA SKLQNELDNV STLLEEAEKK GIKFAKDAAS L
Target Information
MYH10 encodes a member of the myosin superfamily. The protein represents a conventional non-muscle myosin; it should not be confused with the unconventional myosin-10 (MYO10). Myosins are actin-dependent motor proteins with diverse functions including regulation of cytokinesis, cell motility, and cell polarity. Mutations in this gene have been associated with May-Hegglin anomaly and developmental defects in brain and heart. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cellular myosin heavy chain, type B; flectin; MCH-B(B2); Myosin heavy chain 10; myosin heavy chain 10, non-muscle; Myosin heavy chain, non-muscle IIb; myosin heavy chain, nonmuscle type B; myosin heavy chain, nonmuscular, type B; myosin IIB; myosin, heavy chain 10, non-muscle; myosin, heavy polypeptide 10, non-muscle; Myosin-10; NMMHC II-b; NMMHC IIB; NMMHC-B; NMMHC-IIB; Non-muscle myosin heavy chain B; Non-muscle myosin heavy chain IIb; nonmuscle myosin; nonmuscle myosin heavy chain II-B; nonmuscle myosin heavy chain IIB; nonmuscle myosin heavy chain-B; nonmuscle myosin II heavy chain-B; OTTHUMP00000165799
Gene Aliases: 5730504C04Rik; 9330167F11Rik; Fltn; MCH-B; mKIAA3005; MYH10; Myhn-2; Myhn2; NMHC II-B; NMHC-B; NMHCII-B; NMMHC II-b; NMMHC-B; NMMHC-IIB; NMMHCB; SMemb
UniProt ID: (Human) P35580, (Mouse) Q61879, (Rat) Q9JLT0
Entrez Gene ID: (Human) 4628, (Mouse) 77579, (Rat) 79433
mitotic cytokinesis
in utero embryonic development
neuron migration
plasma membrane repair
exocytosis
substrate-dependent cell migration, cell extension
nuclear migration
cell adhesion
axonogenesis
axon guidance
brain development
adult heart development
metabolic process
cell proliferation
regulation of cell shape
fourth ventricle development
lateral ventricle development
third ventricle development
cerebellar Purkinje cell layer development
actin cytoskeleton organization
actin filament-based movement
myofibril assembly
actomyosin structure organization
neuron projection development
neuromuscular process controlling balance
cardiac myofibril assembly
ventricular cardiac muscle cell development
retina development in camera-type eye
cardiac septum development
heart development
aorta development
viral entry into host cell
positive regulation of protein secretion
cardiac muscle cell proliferation
coronary vasculature development
postsynaptic actin cytoskeleton organization
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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