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Invitrogen
MYH10 Polyclonal Antibody
Advanced Verification
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
Product Details
PA5-61541
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
0.04-0.4 µg/mL | - |
Immunohistochemistry (IHC) |
1:1,000-1:2,500 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant protein corresponding to Human MYH10 |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.1 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.2, with 40% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2644338 |
Product Specific Information
Immunogen sequence: RQLDDATEAN EGLSREVSTL KNRLRRGGPI SFSSSRSGRR QLHLEGASLE LSDDDTESKT SDVNETQPPQ
Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 97%.
Target Information
MYH10 encodes a member of the myosin superfamily. The protein represents a conventional non-muscle myosin; it should not be confused with the unconventional myosin-10 (MYO10). Myosins are actin-dependent motor proteins with diverse functions including regulation of cytokinesis, cell motility, and cell polarity. Mutations in this gene have been associated with May-Hegglin anomaly and developmental defects in brain and heart. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cellular myosin heavy chain, type B; Myosin heavy chain 10; Myosin heavy chain, non-muscle IIb; myosin heavy chain, nonmuscle type B; myosin, heavy polypeptide 10, non-muscle; Myosin-10; NMMHC II-b; NMMHC IIB; NMMHC-B; Non-muscle myosin heavy chain B; Non-muscle myosin heavy chain IIb; nonmuscle myosin; nonmuscle myosin heavy chain IIB; nonmuscle myosin II heavy chain-B; OTTHUMP00000165799
Gene Aliases: MYH10; NMMHC-IIB; NMMHCB
UniProt ID: (Human) P35580
Entrez Gene ID: (Human) 4628
mitotic cytokinesis
in utero embryonic development
neuron migration
plasma membrane repair
cardiac septum development
exocytosis
substrate-dependent cell migration, cell extension
nuclear migration
cell adhesion
axon guidance
adult heart development
cell proliferation
regulation of cell shape
fourth ventricle development
lateral ventricle development
third ventricle development
cerebellar Purkinje cell layer development
actin filament-based movement
actomyosin structure organization
aorta development
neuromuscular process controlling balance
cardiac myofibril assembly
ventricular cardiac muscle cell development
retina development in camera-type eye
coronary vasculature development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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