Positive Control: 293T, A431, HeLa, HepG2, MYH10-transfected 293T
Predicted Reactivity: Mouse (100%), Rat (100%), Bovine (100%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
MYH10 encodes a member of the myosin superfamily. The protein represents a conventional non-muscle myosin; it should not be confused with the unconventional myosin-10 (MYO10). Myosins are actin-dependent motor proteins with diverse functions including regulation of cytokinesis, cell motility, and cell polarity. Mutations in this gene have been associated with May-Hegglin anomaly and developmental defects in brain and heart. Multiple transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: Cellular myosin heavy chain, type B; Myosin heavy chain 10; Myosin heavy chain, non-muscle IIb; myosin heavy chain, nonmuscle type B; myosin, heavy polypeptide 10, non-muscle; Myosin-10; NMMHC II-b; NMMHC IIB; NMMHC-B; Non-muscle myosin heavy chain B; Non-muscle myosin heavy chain IIb; nonmuscle myosin; nonmuscle myosin heavy chain IIB; nonmuscle myosin II heavy chain-B; OTTHUMP00000165799
Gene Aliases: MYH10; NMMHC-IIB; NMMHCB
UniProt ID: (Human) P35580
Entrez Gene ID: (Human) 4628