Positive Control: 293T, A431, HeLa, HepG2, MYH10-transfected 293T
Predicted Reactivity: Mouse (100%), Rat (100%), Bovine (100%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
MYH10 encodes a member of the myosin superfamily. The protein represents a conventional non-muscle myosin; it should not be confused with the unconventional myosin-10 (MYO10). Myosins are actin-dependent motor proteins with diverse functions including regulation of cytokinesis, cell motility, and cell polarity. Mutations in this gene have been associated with May-Hegglin anomaly and developmental defects in brain and heart. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cellular myosin heavy chain, type B; heavy chain 10; myosin; Myosin heavy chain 10; Myosin heavy chain, non-muscle IIb; myosin heavy chain, nonmuscle type B; myosin, heavy polypeptide 10, non-muscle; Myosin-10; NMMHC II-b; NMMHC IIB; NMMHC-B; NMMHCB; non-muscle; Non-muscle myosin heavy chain B; Non-muscle myosin heavy chain IIb; nonmuscle myosin heavy chain IIB; nonmuscle myosin II heavy chain-B
Gene Aliases: MYH10; NMMHC-IIB; NMMHCB
UniProt ID: (Human) P35580
Entrez Gene ID: (Human) 4628