PA5-27506 targets MYH9 in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-27506 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 184 of Human MYH9.
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This gene encodes a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain. The protein is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in MYH9 are the cause of non-syndromic sensorineural deafness autosomal dominant type 17, Epstein syndrome, Alport syndrome with macrothrombocytopenia, Sebastian syndrome, Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness.
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Protein Aliases: BDPLT6; cellular myosin heavy chain; Cellular myosin heavy chain, type A; DFNA17; EPSTS; FTNS; MHA; myosin heavy chain; Myosin heavy chain 9; Myosin heavy chain, non-muscle IIa; Myosin-9; NMHC-II-A; NMMHC II-a; NMMHC-A; NMMHC-IIA; NMMHCA; non-muscle IIa; non-muscle myosin heavy chain 9; Non-muscle myosin heavy chain A; Non-muscle myosin heavy chain IIa; non-muscle myosin heavy polypeptide 9; nonmuscle myosin heavy chain II-A; type A
Gene Aliases: BDPLT6; DFNA17; EPSTS; FTNS; MHA; MYH9; NMHC-II-A; NMMHC-IIA; NMMHCA
UniProt ID: (Human) P35579
Entrez Gene ID: (Human) 4627