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          • Primary Antibodies ›
          • MYO15A Antibodies

          Invitrogen

          MYO15A Polyclonal Antibody

          View all (4) MYO15A antibodies

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          Cite MYO15A Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (1)
          MYO15A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          MYO15A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          MYO15A Antibody (PA5-144363) in IHC (P)

          Immunohistochemistry analysis with a MYO15A polyclonal antibody (Product # PA5-144363) using a dilution of 1:200 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30 min at RT. Then primary antibody (1% BSA) was incu... View More {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          View Product

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          MYO15A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          MYO15A Polyclonal Antibody

          Product Details

          PA5-144363

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:200-1:500
          -

          ELISA (ELISA)

          Assay-dependent
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant Human Unconventional myosin-XV protein (237-451AA)
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          3.27 mg/mL

          Amount

          327 µg

          Purification

          Protein G

          Storage buffer

          PBS, pH 7.4, with 50% glycerol

          Contains

          0.03% Proclin 300

          Storage conditions

          -20°C or -80°C if preferred

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_3091531

          Target Information

          This gene encodes an unconventional myosin. This protein differs from other myosins in that it has a long N-terminal extension preceding the conserved motor domain. Studies in mice suggest that this protein is necessary for actin organization in the hair cells of the cochlea. Mutations in this gene have been associated with profound, congenital, neurosensory, nonsyndromal deafness. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Read-through transcripts containing an upstream gene and this gene have been identified, but they are not thought to encode a fusion protein. Several alternatively spliced transcript variants have been described, but their full length sequences have not been determined. [provided by RefSeq, Jul 2008].

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: myosin-XV; Unconventional myosin-15; Unconventional myosin-XV; unnamed protein product

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          Gene Aliases: DFNB3; MYO15; MYO15A

          View more View less

          UniProt ID: (Human) Q9UKN7

          View more View less

          Entrez Gene ID: (Human) 51168

          View more View less

          Function(s)
          microfilament motor activity nucleotide binding motor activity actin binding calmodulin binding ATP binding actin filament binding
          Process(es)
          endocytosis actin filament organization sensory perception of sound locomotory behavior response to light stimulus inner ear morphogenesis
          It has to be done as per old AB suggested Products section.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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