Immunogen sequence: ENAFFLDHVR TSFLLNLRRQ LPQNVLDTSW PTPPPALREA SELLRELCIK NMVWKYCRSI SPEWKQQLQQ KAVASEIFKG KKDNYPQSVP RLFISTRLGT DEISPRVLQA LGSEPIQYAV PVVKYDRKGY KPRSRQLLLT PNAVVIVEDA KVKQRIDYAN LTGISVSSLS DSLFVLHVQR ADNKQKGDVV LQSDHVIETL TKTALSANRV NSININQGSI TFAGGPGRDG TIDFTPGSEL LITKAKNGHL AVVAPRLNSR; Positive Samples: HT-29, SKOV3, Mouse lung, Rat lung; Cellular Location: Cell membrane, Cell projection, Cytoplasm, Cytoplasmic side, Cytoplasmic vesicle, Nucleus, Nucleus, Peripheral membrane protein, nuclear pore complex, nucleolus, nucleoplasm, ruffle, stereocilium membrane
MYO1C is a member of the unconventional myosin protein family, which are actin-based molecular motors. The protein is found in the cytoplasm, and one isoform with a unique N-terminus is also found in the nucleus. The nuclear isoform associates with RNA polymerase I and II and functions in transcription initiation. The mouse ortholog of this protein also functions in intracellular vesicle transport to the plasma membrane.
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Protein Aliases: MMI-beta; MMIb; Myosin heavy chain myr 2; Myosin I beta; myosin IC-like; myosin-I beta; myosin-Ibeta; myosin-Ic; nuclear myosin I; nuclear myosin I beta; unconventional myosin Myr2 I heavy chain; Unconventional myosin-Ic
Gene Aliases: C80397; mm1beta; MMI-beta; MMIb; MYO1C; MYO1E; Myr2; NMI