Unconventional myosin that functions as actin-based motor protein with ATPase activity. Plays a role in endosomal protein trafficking, and especially in the transfer of cargo proteins from early to recycling endosomes. Required for normal planar cell polarity in ciliated tracheal cells, for normal rotational polarity of cilia, and for coordinated, unidirectional ciliary movement in the trachea. Required for normal, polarized cilia organization in brain ependymal epithelial cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: myo1d; myosin 1C; Myosin heavy chain myr 4; myosin IC; myosin-I gamma; myosin-Id; myosin1C; protein phosphatase 1, regulatory subunit 108; Unconventional myosin from rat 4 for myosin I heavy chain; Unconventional myosin-Id
Gene Aliases: 9930104H07Rik; AW544947; D11Ertd9e; KIAA0727; Myo1c; MYO1D; myosin-1d; Myr2; Myr4; PPP1R108