Invitrogen

MYO5A Polyclonal Antibody

Advanced Verification

This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.

View all (7) MYO5A antibodies

Datasheet

Protocols

Questions & Answers

Tech Support

Datasheet

Protocols

Questions & Answers

Tech Support

Antibody Testing Data (1)
Advanced Verification (1)

MYO5A Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 2

MYO5A Antibody (PA5-81932) in ICC/IF

Immunofluorescent analysis of MYO5A in A-431 cells using a MYO5A polyclonal antibody (Product # PA5-81932). The analysis shows localization to microtubule organizing center & focal adhesion sites.

Product Image Gallery

MYO5A Antibody — Relative expression in different tissues in IHC: Detection of differential expression levels of MYO5A demonstrates antibody specificity. Immunohistochemical analysis of MYO5A using anti-MYO5A Polyclonal Antibody (Product # PA5-81932), shows significant staining of MYO5A in cerebral cortex and shows minimal or weak staining in liver tissues. The relative expression levels of MYO5A within each tissue is shown using RNA-Seq. {RE}

Product Details

PA5-81932

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human MYO5A

View immunogen

Conjugate

Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Anitgen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

RRID

AB_2789093

Product Specific Information

Immunogen sequence: QNLQLPPEAR IEASLQHEIT RLTNENLDLM EQLEKQDKTV RKLKKQLKVF AKKIGELEVG QMENISPGQI IDEPIRPVNI PRKEKDFQGM LEYKKEDEQK LVKNLILELK PRGVAVNLIP G

Target Information

This gene is one of three myosin V heavy-chain genes, belonging to the myosin gene superfamily. Myosin V is a class of actin-based motor proteins involved in cytoplasmic vesicle transport and anchorage, spindle-pole alignment and mRNA translocation. The protein encoded by this gene is abundant in melanocytes and nerve cells. Mutations in this gene cause Griscelli syndrome type-1 (GS1), Griscelli syndrome type-3 (GS3) and neuroectodermal melanolysosomal disease, or Elejalde disease. Multiple alternatively spliced transcript variants encoding different isoforms have been reported, but the full-length nature of some variants has not been determined.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?

Let us know so we can reference it here.

Cite this product

Bioinformatics

Protein Aliases: Dilute myosin heavy chain, non-muscle; Myosin heavy chain 12; myosin V; myosin VA (heavy chain 12, myoxin); myosin, heavy polypeptide kinase; Myosin-12; myosin-Va; Myoxin; OTTMUSP00000017756; OTTMUSP00000019176; OTTMUSP00000046608; Unconventional myosin-Va

Gene Aliases: GS1; MYH12; MYO5; MYO5A; MYR12

UniProt ID: (Human) Q9Y4I1

Entrez Gene ID: (Human) 4644

Molecular Function: actin binding motor protein