This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: NLMKKELEEE RSRYQNLVKE YSQLEQRYDN LRDEMTIIKQ TPGHRRNPSN QSSLESDSNY PSISTSEIGD TEDALQQVEE IGLEKAAMDM TVFLK
Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 89%.
May be involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation. Required in a complex with RAB11A and RAB11FIP2 for the transport of NPC1L1 to the plasma membrane. Together with RAB11A participates in CFTR trafficking to the plasma membrane and TF (transferrin) recycling in nonpolarized cells. Together with RAB11A and RAB8A participates in epithelial cell polarization. Together with RAB25 regulates transcytosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: MYO5B variant protein; myosin-Vb; Unconventional myosin-Vb
Gene Aliases: KIAA1119; MYO5B
UniProt ID: (Human) Q9ULV0
Entrez Gene ID: (Human) 4645