Search
Proteintech
MYO9B Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
12432-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MYO9B Fusion Protein Ag3108 (1660-1983 aa encoded by BC018108)
Conjugate
Form
Liquid
Concentration
0.33 mg/mL
Amount
49.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: DKALLCSVC KMTCHKKCVH KIQSHCSYTY GRKGEPGVEP GHFGVCVDSL TSDKASVPIV LEKLLEHVEM HGLYTEGLYR KSGAANRTRE LRQALQTDPA AVKLENFPIH AITGVLKQWL RELPEPLMTF AQYGDFLRAV ELPEKQEQLA AIYAVLEHLP EANHNSLERL IFHLVKVALL EDVNRMSPGA LAIIFAPCLL RCPDNSDPLT SMKDVLKITT CVEMLIKEQM RKYKVKMEEI SQLEAAESIA FRRLSLLRQN APWPLKLGFS SPYEGVLNKS PKTRDIQEEE LEVLLEEEAA GGDEDREKEI LIERIQSIKE EKEDI (1660-1983 aa encoded by BC018108 )
Target Information
This gene encodes a member of the myosin family of actin-based molecular motor heavy chain proteins. The protein has four IQ motifs located in the neck domain that bind calmodulin, which serves as a light chain. The protein complex has a single-headed structure and exhibits processive movement on actin filaments toward the minus-end. The protein also has rho-GTPase activity. Polymorphisms in this gene are associated with celiac disease and ulcerative colitis susceptibility. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: celiac disease 4; myosin; myosin-IXb; myr 5; Unconventional myosin from rat 3; Unconventional myosin-9b; Unconventional myosin-IXb; unnamed protein product
Gene Aliases: CELIAC4; MYO9B; MYR5
UniProt ID: (Human) Q13459
Entrez Gene ID: (Human) 4650, (Mouse) 17925, (Rat) 25486
microfilament motor activity
nucleotide binding
motor activity
actin binding
GTPase activator activity
protein binding
calmodulin binding
ATP binding
zinc ion binding
ATPase activity
small GTPase binding
protein homodimerization activity
ADP binding
metal ion binding
Roundabout binding
actin filament binding
actin-dependent ATPase activity
ATP-dependent protein binding
signal transduction
Rho protein signal transduction
actin filament-based movement
ARF protein signal transduction
regulation of Rho protein signal transduction
Roundabout signaling pathway
intracellular signal transduction
regulation of small GTPase mediated signal transduction
lamellipodium morphogenesis
monocyte chemotaxis
metabolic process
establishment of cell polarity
actin-myosin filament sliding
positive regulation of GTPase activity
macrophage chemotaxis
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support