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Proteintech
MYO9B Polyclonal Antibody
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Product Details
12432-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MYO9B Fusion Protein Ag3108 (1660-1983 aa encoded by BC018108)
Conjugate
Form
Liquid
Concentration
0.33 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: DKALLCSVC KMTCHKKCVH KIQSHCSYTY GRKGEPGVEP GHFGVCVDSL TSDKASVPIV LEKLLEHVEM HGLYTEGLYR KSGAANRTRE LRQALQTDPA AVKLENFPIH AITGVLKQWL RELPEPLMTF AQYGDFLRAV ELPEKQEQLA AIYAVLEHLP EANHNSLERL IFHLVKVALL EDVNRMSPGA LAIIFAPCLL RCPDNSDPLT SMKDVLKITT CVEMLIKEQM RKYKVKMEEI SQLEAAESIA FRRLSLLRQN APWPLKLGFS SPYEGVLNKS PKTRDIQEEE LEVLLEEEAA GGDEDREKEI LIERIQSIKE EKEDI (1660-1983 aa encoded by BC018108 )
Target Information
This gene encodes a member of the myosin family of actin-based molecular motor heavy chain proteins. The protein has four IQ motifs located in the neck domain that bind calmodulin, which serves as a light chain. The protein complex has a single-headed structure and exhibits processive movement on actin filaments toward the minus-end. The protein also has rho-GTPase activity. Polymorphisms in this gene are associated with celiac disease and ulcerative colitis susceptibility. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: celiac disease 4; myosin; myosin-IXb; myr 5; Unconventional myosin from rat 3; unconventional myosin IXb; Unconventional myosin-9b; Unconventional myosin-IXb
Gene Aliases: CELIAC4; MYO9B; MYR5
UniProt ID: (Human) Q13459
Entrez Gene ID: (Human) 4650, (Mouse) 17925, (Rat) 25486
microfilament motor activity
actin binding
GTPase activator activity
protein binding
calmodulin binding
ATP binding
zinc ion binding
ATPase activity
Rho GTPase binding
actin-dependent ATPase activity
protein homodimerization activity
ATP-dependent protein binding
ADP binding
Roundabout binding
actin filament binding
nucleotide binding
motor activity
metal ion binding
Rho protein signal transduction
actin filament-based movement
ARF protein signal transduction
regulation of Rho protein signal transduction
Roundabout signaling pathway
positive regulation of GTPase activity
regulation of small GTPase mediated signal transduction
monocyte chemotaxis
signal transduction
metabolic process
establishment of cell polarity
actin-myosin filament sliding
intracellular signal transduction
macrophage chemotaxis
lamellipodium morphogenesis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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