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Bethyl Laboratories
MYT1 Polyclonal Antibody
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FIGURE: 1 / 1
MYT1 Antibody (A302-424A) in WB
Detection of human MYT1 by western blot and immunoprecipitation. Samples: Whole cell lysate from HeLa (5, 15 and 50 µg for WB; 1 mg for IP, 20% of IP loaded) and HEK293T (T; 50 µg) cells. Antibodies: Affinity purified rabbit anti-MYT1 antibody (Product # A302-424A) used for WB at 0.04 µg/mL (A) and 1 µg/mL (B) and used for IP at 3 µg/mg lysate. Detection: Chemiluminescence with exposure times of 30 seconds (A) and 10 seconds (B).
Product Details
A302-424A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 449 and 499 of human membrane associated tyrosine/threonine 1.
Conjugate
Form
Liquid
Concentration
0.20 mg/mL
Amount
20 µg
Purification
Antigen affinity chromatography
Storage buffer
TBS, pH 7.0 to 8.0, with 0.1% BSA
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
PKMYT1 serine/threonine kinase is a member of a family of neural specific, zinc finger-containing DNA-binding proteins which binds to the promoter regions of proteolipid proteins of the central nervous system and plays a role in the developing nervous system. MYT1 of the oligodendrocyte lineage, along with a closely related CCHC zinc finger, is expressed in developing neurons in the mammalian central nervous system. The recombinant PKMYT1 fragments containing either the upstream 2 zinc fingers or the downstream 4 zinc fingers bound the same cis regulatory element in the PLP1 promoter in vitro and DNA binding required Zn2+, but not other divalent cations.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase; Myt1 kinase; protein phosphatase 1, regulatory subunit 126; unnamed protein product
Gene Aliases: MYT1; PKMYT1; PPP1R126
UniProt ID: (Human) Q99640
Entrez Gene ID: (Human) 9088
regulation of cyclin-dependent protein serine/threonine kinase activity
G2/M transition of mitotic cell cycle
mitotic cell cycle
regulation of mitotic nuclear division
negative regulation of G2/M transition of mitotic cell cycle
meiotic cell cycle
negative regulation of G2/MI transition of meiotic cell cycle
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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