MYT1L, myelin transcription factor 1 family, to which the myelin transcription factor 1-like protein (MYT1L) belongs, is expressed primarily in the developing central nervous system and recruits histone deacetylase (HDAC) to regulate neural transcription. Both MYT1L and the related protein MYT1 interact with SIN3B, a protein that mediates transcriptional repression by binding to HDACs, suggesting that the MYT1 family favor the silencing of genes during neural development. Recent studies suggest that polymorphisms of MYT1L may be associated with schizophrenia.
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Protein Aliases: KIAA1106; Myelin transcription factor 1-like protein; MyT1 L; MyT1-L; MYT1L; neural zinc finger transcription factor 1; NZF1
Gene Aliases: KIAA1106; MRD39; MYT1L; NZF1; ZC2H2C2; ZC2HC4B
UniProt ID: (Human) Q9UL68
Entrez Gene ID: (Human) 23040