A suggested positive control is mouse brain tissue lysate.
PA5-34468 can be used with blocking peptide PEP-1510.
The myelin transcription factor 1 family, to which the myelin transcription factor 1-like protein (MYT1L) belongs, is expressed primarily in the developing central nervous system and recruits histone deacetylase (HDAC) to regulate neural transcription. Both MYT1L and the related protein MYT1 interact with SIN3B, a protein that mediates transcriptional repression by binding to HDACs, suggesting that the MYT1 family favor the silencing of genes during neural development. Recent studies suggest that polymorphisms of MYT1L may be associated with schizophrenia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Myelin transcription factor 1-like protein; MyT1-L; MYT1L; Neural zinc finger factor 1; neural zinc finger protein NZF-1; neural zinc finger transcription factor 1; NZF-1; NZF1; NZTF1; PMNG1; PNG-1; postmeiotic neural gene 1; Postmitotic neural gene 1 protein; Zinc finger protein Png-1
Gene Aliases: 2900046C06Rik; 2900093J19Rik; C630034G21Rik; KIAA1106; mKIAA1106; MRD39; MYT1L; Nzf-1; NZF1; Nztf1; Pmng1; Png-1; Png1; ZC2H2C2; ZC2HC4B