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Invitrogen
MZB1 Polyclonal Antibody
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FIGURE: 1 / 7
MZB1 Antibody (PA5-84122) in IHC (P)
Immunohistochemistry analysis of MZB1 in human liver, lymph node, placenta and small intestine. Samples were incubated with MZB1 polyclonal antibody (Product # PA5-84122). Shows similar protein distribution across tissues to independent MZB1 antibody (Product # PA5-60493) (B).
Product Details
PA5-84122
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human MZB1. Recombinant protein control fragment (Product #RP-104951).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Amount
5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: TATAPQLDDE EMYSAHMPAH LRCDACRAVA YQMWQNLAKA ETKLHTSNSG GRRELSELVY TDVLDRS
Highest antigen sequence indentity to the following orthologs: Rat - 73%, Mouse - 72%.
Target Information
MZB1 associates with immunoglobulin M (IgM) heavy and light chains and promotes IgM assembly and secretion. May exert its effect by acting as a molecular chaperone or as an oxidoreductase as it displays a low level of oxidoreductase activity. Isoform 2 may be involved in regulation of apoptosis. Helps to diversify peripheral B-cell functions by regulating Ca(2+) stores, antibody secretion and integrin activation.; Acts as a hormone-regulated adipokine/proinflammatory cytokine that is implicated in causing chronic inflammation, affecting cellular expansion and blunting insulin response in adipocytes. May have a role in the onset of insulin resistance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: caspase-2 binding protein; HSPC190; Marginal zone B- and B1-cell-specific protein; MEDA-7; Mesenteric estrogen-dependent adipose 7; mesenteric oestrogen-dependent adipose gene- 7; MGC29506; PACAP; caspase-2 binding protein; pERp1; plasma cell-induced ER protein 1; Plasma cell-induced resident endoplasmic reticulum protein; Plasma cell-induced resident ER protein; Proapoptotic caspase adapter protein; proapoptotic caspase adaptor protein; unnamed protein product
Gene Aliases: HSPC190; MEDA-7; MEDA7; MZB1; PACAP; pERp1
UniProt ID: (Human) Q8WU39
Entrez Gene ID: (Human) 51237
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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