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Bethyl Laboratories

Mdc1/Nfbd1 Polyclonal Antibody

View all (17) MDC1 antibodies
635D49A6-4B57-425E-8DC4-6BA1AEB7B473 Created with sketchtool. Datasheet
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635D49A6-4B57-425E-8DC4-6BA1AEB7B473 Created with sketchtool. Datasheet
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C488C313-B559-4BFD-B17D-A8B65492815A Created with sketchtool. Tech Support

Product Details

Tested Applications
Dilution
Immunoprecipitation (IP)
2-10 µg/mg lysate
Product Specifications
Species Reactivity
Mouse
Host / Isotype
Rabbit / IgG
Class
Polyclonal
Type
Antibody
Immunogen
Between 900 and 950
Conjugate
Unconjugated
Form
liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
phosphate/tris citrate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4° C

Product Specific Information

The recommended shelf life for this product is 1 year from date of receipt.

Target Information

The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: DAAP-285E11.7; DKFZp781A0122; KIAA0170; mediation of DNA damage checkpoint 1; Mediator of DNA damage checkpoint protein 1; MGC166888; NFBD1

Gene Aliases: 6820401C03; AA413496; Kiaa0170; Mdc1; mKIAA0170; Nfbd1

UniProt ID: (Mouse) Q5PSV9

Entrez Gene ID: (Mouse) 240087

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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