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          • Primary Antibodies ›
          • Midkine Antibodies

          Proteintech

          Midkine Polyclonal Antibody

          View all (23) Midkine antibodies

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          Cite Midkine Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (3)
          Midkine Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          Midkine Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 3

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          Midkine Antibody (28546-1-AP) in IHC (P)

          Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using (Product # 28546-1-AP) (Midkine antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
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          View Product

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          Midkine Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Midkine Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Midkine Antibody in Western Blot (WB)

          Product Details

          28546-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:300
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:500
          -
          Product Specifications

          Species Reactivity

          Human, Mouse

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          MDK Fusion Protein Ag29185

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          233 µg/mL

          Amount

          34.95 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice

          Product Specific Information

          Aliquoting is unnecessary for -20°C storage.

          Target Information

          Midkine is a retinoic acid-responsive, heparin-binding growth factor expressed in various cell types during embryogenesis. It promotes angiogenesis, cell growth, and cell migration. Midkine is also expressed in several carcinomas, suggesting that it may play a role in tumorigenesis, perhaps through its effects on angiogenesis.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Amphiregulin-associated protein; ARAP; FLJ27379; Midgestation and kidney protein; Midkine; MK; neurite growth-promoting factor 2; Neurite outgrowth-promoting factor 2; Neurite outgrowth-promoting protein; Retanoic acid-responsive protein; retinoic acid inducible factor; Retinoic acid-induced differentiation factor; retinoic acid-responsive protein

          View more View less

          Gene Aliases: ARAP; MDK; Mek; MK; MK1; NEGF2

          View more View less

          UniProt ID: (Human) P21741, (Mouse) P12025

          View more View less

          Entrez Gene ID: (Human) 4192, (Mouse) 17242

          View more View less

          Function(s)
          protein binding growth factor activity heparin binding chondroitin sulfate binding heparan sulfate binding growth factor
          Process(es)
          behavioral fear response leukocyte chemotaxis involved in inflammatory response T cell activation involved in immune response positive regulation of leukocyte chemotaxis cytoskeleton organization negative regulation of cell adhesion signal transduction nervous system development short-term memory response to xenobiotic stimulus response to wounding response to hormone negative regulation of cardiac muscle cell apoptotic process positive regulation of epithelial to mesenchymal transition positive regulation of macrophage chemotaxis positive regulation of keratinocyte proliferation positive regulation of neuron projection development response to auditory stimulus cell migration dentate gyrus development cerebellar granular layer development hippocampus development cerebral cortex development cell differentiation negative regulation of ossification adrenal gland development positive regulation of cell migration defecation regulation of chondrocyte differentiation positive regulation of interleukin-12 production intracellular signal transduction tissue regeneration negative regulation of neuron apoptotic process estrous cycle positive regulation of T cell differentiation negative regulation of regulatory T cell differentiation positive regulation of cell adhesion positive regulation of transcription, DNA-templated regulation of bone remodeling oogenesis positive regulation of oligodendrocyte differentiation positive regulation of inflammatory response regulation of behavior response to glucocorticoid positive regulation of cell division positive regulation of cartilage development positive regulation of smooth muscle cell chemotaxis positive regulation of neutrophil chemotaxis negative regulation of canonical Wnt signaling pathway negative regulation of inflammatory response to wounding positive regulation of inflammatory response to wounding glial cell projection elongation positive regulation of substrate adhesion-dependent cell spreading positive regulation of leukocyte cell-cell adhesion negative regulation of epithelial cell apoptotic process positive regulation of leukocyte adhesion to vascular endothelial cell positive regulation of blood vessel branching positive regulation of vascular endothelial cell proliferation positive regulation of artery morphogenesis positive regulation of neural precursor cell proliferation positive regulation of hepatocyte proliferation positive regulation of neutrophil extravasation positive regulation of neuron migration multicellular organism development negative regulation of neuron death
          It has to be done as per old AB suggested Products section.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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          Host server : magellan-search-blue-67655d8755-zsnhf:80/100.66.75.14:80.
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