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Invitrogen
Myc Tag Polyclonal Antibody
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Product Details
PA3-981
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Tag
Published species
Tag
Host/Isotype
Sheep
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to residues M E Q K L I S E E D L G C of human c-Myc.
Conjugate
Form
Liquid
Concentration
Conc. Not Determined
Storage buffer
PBS, pH 7.4
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
PA3-981 detects c-Myc tagged proteins.
PA3-981 has been successfully used in immunofluorescence, immunoprecipitation, and Western blot procedures. By Western blot it detects a ~41 kDa protein representing c-Myc.
The PA3-981 immunogen is a synthetic peptide corresponding to residues M E Q K L I S E E D L G C of human c-Myc.
Target Information
Myc is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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