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Invitrogen
NADK Polyclonal Antibody
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FIGURE: 1 / 6
NADK Antibody (PA5149837) in IHC (P)
Immunohistochemistry analysis of NADK in paraffin-embedded Human Stomach tissue. Samples were incubated with NADK Polyclonal (Product # PA5149837) antibody using a dilution of 10 µg/mL, followed by HRP-Linked Caprine Anti-Rabbit IgG (2 µg/mL) and DAB.
Product Details
PA5149837
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Pig,
Rat
Host/Isotype
Rabbit
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant NAD Kinase (NADK) (Leu187-His426)
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
NADK (Nicotinamide Adenine Dinucleotide Kinase) is an enzyme crucial in the regulation of intracellular NADP+ levels, which are necessary for metabolic processes such as fatty acid and DNA synthesis. The human NADK gene is located on chromosome 1p36.33 and encodes a protein that primarily functions in the cytoplasm. NADK catalyzes the phosphorylation of NAD+ to NADP+, playing a significant role in maintaining the cellular redox state. Structurally, human NADK forms a dimeric organization, as revealed by its crystal structure, and includes four subunits (chains A-D) with specific colors indicating different chains. The enzyme's activity is regulated post-translationally, but its pathophysiological significance in humans remains underexplored. Multiple orthologs of the NADK gene are present in various organisms, illustrating its evolutionary conservation and importance across different species.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ13052; NAD kinase; NAD kinase tv1; Poly(P)/ATP NAD kinase; ppnk; Putative inorganic polyphosphate/ATP-NAD kinase (Poly(P)/ATP NAD kinase); unnamed protein product
Gene Aliases: 4432404C02Rik; BC004012; dJ283E3.1; NADK; NADK1
UniProt ID: (Human) O95544, (Mouse) P58058
Entrez Gene ID: (Pig) 110261345, (Human) 65220, (Rat) 100125370, (Mouse) 192185
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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