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Invitrogen
NAGLU Polyclonal Antibody
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Product Details
PA5-28261
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human NAGLU. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.69 mg/mL
Amount
69 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Predicted reactivity: Mouse (86%), Bovine (89%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes an enzyme that degrades heparan sulfate by hydrolysis of terminal N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides. Defects in this gene are the cause of mucopolysaccharidosis type IIIB (MPS-IIIB), also known as Sanfilippo syndrome B. This disease is characterized by the lysosomal accumulation and urinary excretion of heparan sulfate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Alpha-N-acetylglucosaminidase; alpha-N-acetylglucosaminidase, lysosomal; N-acetyl-alpha-glucosaminidase; N-acetyl-glucosaminidase; N-acetylglucosaminidase, alpha; NAG; testicular tissue protein Li 18
Gene Aliases: CMT2V; MPS-IIIB; MPS3B; NAG; NAGLU; RGD1564228; UFHSD; UFHSD1
UniProt ID: (Human) P54802
Entrez Gene ID: (Human) 4669, (Rat) 360630, (Mouse) 27419
lysosome organization
cerebellar Purkinje cell layer development
middle ear morphogenesis
locomotor rhythm
retinal rod cell development
inner ear receptor cell development
ganglioside metabolic process
microglial cell activation
liver development
vasculature development
endothelium development
heart valve development
mitral valve morphogenesis
left ventricular cardiac muscle tissue morphogenesis
proteoglycan metabolic process
superoxide metabolic process
autophagy
inflammatory response
cytoplasm organization
Golgi organization
vacuole organization
nervous system development
heart development
locomotory behavior
determination of adult lifespan
glycoprotein metabolic process
response to wounding
gene expression
microglia differentiation
lipid catabolic process
protein processing
nerve development
neurogenesis
heparan sulfate proteoglycan catabolic process
heparan sulfate proteoglycan metabolic process
heparin metabolic process
glycosaminoglycan metabolic process
adult behavior
hair follicle morphogenesis
response to lipopolysaccharide
collagen metabolic process
toll-like receptor 4 signaling pathway
response to disaccharide
cellular response to oxidative stress
maintenance of blood-brain barrier
exploration behavior
aorta development
aorta morphogenesis
hormone metabolic process
amyloid precursor protein metabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
astrocyte activation
astrocyte differentiation
system development
cardiac muscle cell development
retina development in camera-type eye
limb development
multicellular organismal iron ion homeostasis
motor behavior
receptor signaling pathway via STAT
vesicle tethering
neuroinflammatory response
carbohydrate derivative metabolic process
rod bipolar cell differentiation
cone retinal bipolar cell differentiation
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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