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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 252 and 487 of Human NAGLU|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-30097 targets NAGLU in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-30097 immunogen is recombinant fragment corresponding to a region within amino acids 252 and 487 of Human NAGLU.
This gene encodes an enzyme that degrades heparan sulfate by hydrolysis of terminal N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides. Defects in this gene are the cause of mucopolysaccharidosis type IIIB (MPS-IIIB), also known as Sanfilippo syndrome B. This disease is characterized by the lysosomal accumulation and urinary excretion of heparan sulfate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
alpha-N-acetylglucosaminidase; MPS-IIIB; MPS3B; N-acetylglucosaminidase, alpha; NAG; testicular tissue protein Li 18; UFHSD
CMT2V; MPS-IIIB; MPS3B; NAG; NAGLU; UFHSD; UFHSD1