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|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A 16 amino acid peptide near the amino terminus of human NALP14.|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Western Blot (WB)||1 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
A suggested positive control is rat brain tissue lysate.
PA5-21029 can be used with blocking peptide PEP-1143.
NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP14 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. While little is known about the function of NALP14, it has been suggested that it may play a role in spermatogenesis and that mutations in the NALP14 gene might cause spermatogenic failure.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
CLR11.2, GC-LRR, NALP14, NOD5, PAN8; germ cell specific leucine-rich repeat NTPase; germ-cell specific leucine rich repeat NTPase; NACHT, leucine rich repeat and PYD containing 14; NACHT, LRR and PYD containing protein 14; NACHT, LRR and PYD domains-containing protein 14; NLR family, pyrin domain containing 14; nucleotide-binding oligomerization domain protein 5; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 14; RNI-like protein
4921520L01Rik; CLR11.2; GC-LRR; Nalp-iota; NALP14; Nalp14l; NLRP14; NOD5; PAN8