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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide (348 KQRLERGEDLEINSQNT 364) of NALP9 protein.|
|Storage buffer||PBS with 0.05% BSA|
|Contains||0.05% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||5 µg/ml|
|Western Blot (WB)||4-6 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
NALP9 is a cytoplasmic protein belonging to the NLRP family with a DAPIN domain, three LRR (leucine-rich) repeats and a NACHT domain. Also called NOD6, NALP9 is a novel intracellular protein involved in inflammation and apoptosis. NALP9 may play a regulatory role in the innate immune system as similar family members belong to the signal-induced multiprotein complex, the inflammasome, which activates the pro-inflammatory caspases, caspase-1 and caspase-5.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
CLR19.1; leucine rich repeat and PYD containing 9; leucine rich repeat and pyrin domain containing 9; LRR and PYD containing protein 9; LRR and PYD domains-containing protein 9; NACHT; NACHT, leucine rich repeat and PYD containing 9; NACHT, LRR and PYD containing protein 9; NALP9; NLR family, pyrin domain containing 9; NOD6; nucleotide-binding oligomerization domain; nucleotide-binding oligomerization domain protein 6; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 9; PAN12; PYRIN and NACHT-containing protein 12
CLR19.1; NALP9; NLRP9; NOD6; PAN12