This Antibody was verified by IP Mass Spectrometry to ensure that the antibody binds to the antigen stated. View Details
PA1-1045 detects Visfatin (PBEF) in human samples.
PA1-1045 has been successfully used in Western blot procedures. In Western blot analysis of human adipose tissue lysate this antibody detects a ~52 kDa protein representing Visfatin.
The PA1-1045 immunogen is a synthetic peptide corresponding to residues S (472) F D E I R K N A Q L N I E L E A A H H (491) of human Visfatin.
The recently discovered adipocytokine Visfatin is a visceral fat specific protein which has been shown to exert insulin-mimetic effects in insulin-sensitive tissues such as liver, muscle and fat. Visfatin can bind to the insulin receptor and visfatin plasma levels increase with obesity. Based on their properties, adipocytokines are likely to play critical roles in metabolic syndromes such as obesity and diabetes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: EC 220.127.116.11; NAmPRTase; NAMPT; Nicotinamide phosphoribosyltransferase; Pre-B cell-enhancing factor; pre-B-cell colony enhancing factor 1; Pre-B-cell colony-enhancing factor 1; Visfatin
Gene Aliases: 1110035O14Rik; NAMPT; PBEF; PBEF1; VF; VISFATIN
UniProt ID: (Human) P43490
Entrez Gene ID: (Human) 10135