Recommended positive controls: A549, HeLa, HepG2, HCT116.
Predicted reactivity: Mouse (85%), Rat (80%), Bovine (87%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Nicotinic acid (NA; niacin) is converted by nicotinic acid phosphoribosyltransferase (NAPRT; EC 126.96.36.199) to NA mononucleotide (NaMN), which is then converted to NA adenine dinucleotide (NaAD), and finally to nicotinamide adenine dinucleotide (NAD), which serves as a coenzyme in cellular redox reactions and is an essential component of a variety of processes in cellular metabolism including response to stress (Hara et al., 2007).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: FHA-HIT-interacting protein; NAPRTase; Nicotinate phosphoribosyltransferase; nicotinate phosphoribosyltransferase domain containing 1; Nicotinate phosphoribosyltransferase domain-containing protein 1; nicotinic acid phosphoribosyltransferase
Gene Aliases: FHIP; NAPRT; NAPRT1; PP3856
UniProt ID: (Human) Q6XQN6
Entrez Gene ID: (Human) 93100