Immunogen sequence: ELGYRAVGVR LDSGDLLQQA QEIRKVFRAA AAQFQVPWLE SVLIVVSNNI DEEALARLAQ EGSEVNVIGI GTSVVTCPQQ PSLGGVYKLV AVGGQPRMKL TEDPEKQTLP GSKAAFRLLG SDGSPLMDML QLAEEPVPQA GQELRVWPPG AQEPCTVRPA QVEPLLRLCL QQGQLCEPLP SLAESRALAQ LSLSRLSPEH RRLRSPAQYQ VVLSERLQAL VNSLCAGQSP; Positive Samples: HepG2, HT-29; Cellular Location: Cytoplasm, cytosol
Nicotinic acid (NA; niacin) is converted by nicotinic acid phosphoribosyltransferase (NAPRT; EC 126.96.36.199) to NA mononucleotide (NaMN), which is then converted to NA adenine dinucleotide (NaAD), and finally to nicotinamide adenine dinucleotide (NAD), which serves as a coenzyme in cellular redox reactions and is an essential component of a variety of processes in cellular metabolism including response to stress (Hara et al., 2007).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: FHA-HIT-interacting protein; NAPRTase; Nicotinate phosphoribosyltransferase; nicotinate phosphoribosyltransferase domain containing 1; Nicotinate phosphoribosyltransferase domain-containing protein 1; nicotinate phosphoribosyltransferase-like protein; nicotinic acid phosphoribosyltransferase
Gene Aliases: 9130210N20Rik; FHIP; NAPRT; NAPRT1; PP3856