This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
Immunogen sequence: DVDSEAKKLL GLGQKHLVMG DIPAAVNAFQ EAASLLGKKY GETANECGEA FFFYGKSLLE LARMENGVLG NALEGVHV
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
NASP encodes a H1 histone binding protein that is involved in transporting histones into the nucleus of dividing cells. Multiple isoforms are encoded by transcript variants of this gene. The somatic form is expressed in all mitotic cells, is localized to the nucleus, and is coupled to the cell cycle. The testicular form is expressed in embryonic tissues, tumor cells, and the testis. In male germ cells, this protein is localized to the cytoplasm of primary spermatocytes, the nucleus of spermatids, and the periacrosomal region of mature spermatozoa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DKFZp547F162; FLJ31599; FLJ35510; histone H1-binding protein; MGC19722; MGC20372; MGC2297; NASP; NASP histone chaperone; Nuclear autoantigenic sperm protein; nuclear autoantigenic sperm protein (histone-binding)
Gene Aliases: FLB7527; HMDRA1; NASP; PRO1999
UniProt ID: (Human) P49321
Entrez Gene ID: (Human) 4678
Molecular Function: chaperone