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Invitrogen
NAT10 Polyclonal Antibody
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FIGURE: 1 / 1
NAT10 Antibody (PA5-50459) in WB
Western Blot analysis of NAT10 was performed using (left to right): A549, K562 and HeLa cells. The membrane was probed using NAT10 Polyclonal Antibody (Product # PA5-50459) 1:200 dilution. Secondary antibody dilution: 1:8,000. Exposure time: 10 seconds.
Product Details
PA5-50459
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Fusion protein corresponding to a region derived from internal residues of human N-acetyltransferase 10 (GCN5-related)
Conjugate
Form
Liquid
Concentration
1.8 mg/mL
Amount
180 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 40% glycerol
Contains
0.05% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
The antibody detects endogenous levels of total NAT10 protein.
Target Information
IRS4 encodes the insulin receptor substrate 4, a cytoplasmic protein that contains many potential tyrosine and serine/threonine phosphorylation sites. Tyrosine-phosphorylated IRS4 protein has been shown to associate with cytoplasmic signalling molecules that contain SH2 domains. The IRS4 protein is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 18S rRNA cytosine acetyltransferase; hALP; N-acetyltransferase 10; N-acetyltransferase 10 (GCN5-related); N-acetyltransferase-like protein; RNA cytidine acetyltransferase; unnamed protein product
Gene Aliases: ALP; KIAA1709; Kre33; NAT10; NET43
UniProt ID: (Human) Q9H0A0
Entrez Gene ID: (Human) 55226
tRNA binding
nucleotide binding
RNA binding
protein binding
ATP binding
N-acetyltransferase activity
transferase activity
transferase activity, transferring acyl groups
transferase activity, transferring acyl groups other than amino-acyl groups
tRNA N-acetyltransferase activity
DNA polymerase binding
mRNA N-acetyltransferase activity
rRNA cytidine N-acetyltransferase activity
rRNA modification
tRNA wobble cytosine modification
rRNA processing
regulation of translation
protein acetylation
tRNA processing
RNA modification
regulation of centrosome duplication
rRNA metabolic process
negative regulation of telomere maintenance via telomerase
ribosome biogenesis
ribosomal small subunit biogenesis
positive regulation of translation
tRNA acetylation
rRNA acetylation involved in maturation of SSU-rRNA
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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