Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
FIGURE: 1 / 1
Immunogen sequence: RKNSARKASI VKNLKDTLGI GKVKRKPSVP DSASPADDSF VDPGERLYDL NMPAYVKFNY MAEREDELSL IKGTKVIVME KCSDGWWRGS YNGQVGWFPS NYVTEEGDSP LGDHVGSLSE KLAAVVNNLN TGQVLHVVQA LYPFSSSNDE ELNFEKGDVM DVIEKPENDP EWWKCRKING MVGLVPKNYV TVMQNNPLTS GLEPSPPQCD YIRPSLTGKF AGNPWYYGKV TRHQAEMALN ERGHEGDFLI RDSESSPNDF SVSLKAQGKN KHFKVQLKET VYCIGQRKFS TMEELVEHYK KAPIFTSEQG EKLYLVKHLS; Positive Samples: Mouse brain; Cellular Location: Cytoplasm, Endoplasmic reticulum, Nucleus
NCK1 is one of the signaling and transforming proteins containing Src homology 2 and 3 (SH2 and SH3) domains. It is located in the cytoplasm and is an adaptor protein involved in transducing signals from receptor tyrosine kinases to downstream signal recipients such as RAS. Alternatively spliced transcript variants encoding different isoforms have been found.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cytoplasmic protein Nck1; MGC12668; NCK adapter protein 1; NCK adaptor protein 1; Nck-1; SH2/SH3 adapter protein Nck1
Gene Aliases: 6330586M15Rik; D230010O13Rik; Nck; Nck-1; Nck1
UniProt ID: (Mouse) Q99M51
Entrez Gene ID: (Mouse) 17973
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support