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Bioss
NCKAP1 Polyclonal Antibody
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Product Details
BS-6204R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human 12 NCKAP1, amino acids 1001-1132.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This gene interacts with Nck and may be involved in the downstream signaling of Nck and shares similarity with the mouse Dhm1 and the yeast dhp1 gene. The yeast gene is involved in homologous recombination and RNA metabolism, such as RNA synthesis and RNA trafficking. Complementation studies show that Dhm1 has a similar function in mouse as dhp1. The function of the human gene has not yet been determined. Transcript variants encoding different isoforms have been noted for this gene; however, their full-length nature is not known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Brain protein H19; Membrane-associated protein HEM-2; MH19; NAP 1; Nck-associated protein 1; p125Nap1
Gene Aliases: C79304; H19; Hem-2; HEM2; KIAA0587; mh19; mKIAA0587; NAP1; NAP125; NCKAP1; p125Nap1
UniProt ID: (Human) Q9Y2A7, (Mouse) Q8CG49, (Rat) P55161
Entrez Gene ID: (Human) 10787, (Mouse) 50884, (Rat) 58823
in utero embryonic development
somitogenesis
neural tube closure
zygotic determination of anterior/posterior axis, embryo
endoderm development
mesodermal cell migration
embryonic body morphogenesis
positive regulation of lamellipodium assembly
Rac protein signal transduction
lamellipodium assembly
notochord development
establishment or maintenance of actin cytoskeleton polarity
regulation of protein localization
embryonic heart tube development
cell migration involved in gastrulation
basal protein localization
apical protein localization
paraxial mesoderm development
paraxial mesoderm morphogenesis
notochord morphogenesis
embryonic foregut morphogenesis
protein stabilization
positive regulation of Arp2/3 complex-mediated actin nucleation
apoptotic process
central nervous system development
viral process
Fc-gamma receptor signaling pathway involved in phagocytosis
vascular endothelial growth factor receptor signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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