FIGURE: 1 / 1
Immunogen sequence: MSRSVLQPSQ QKLAEKLTIL NDRGVGMLTR LYNIKKACGD PKAKPSYLID KNLESAVKFI VRKFPAVETR NNNQQLAQLQ KEKSEILKNL ALYYFTFVDV MEFKDHVCEL LNTIDVCQVF FDITVNFDLT KNYLDLIITY TTLMILLSRI EERKAIIGLY NYAHEMTHGA SDREYPRLGQ MIVDYENPLK KMMEEFVPHS KSLSDALISL QMVYPRRNLS ADQWRNAQLL SLISAPSTML NPAQSDTMPC; Positive Samples: U-87MG, HeLa, MCF7, HepG2, Mouse heart, Rat brain; Cellular Location: Cell membrane, Cell projection, Cytoplasmic side, Single-pass membrane protein, lamellipodium membrane
This gene interacts with Nck and may be involved in the downstream signaling of Nck and shares similarity with the mouse Dhm1 and the yeast dhp1 gene. The yeast gene is involved in homologous recombination and RNA metabolism, such as RNA synthesis and RNA trafficking. Complementation studies show that Dhm1 has a similar function in mouse as dhp1. The function of the human gene has not yet been determined. Transcript variants encoding different isoforms have been noted for this gene; however, their full-length nature is not known.
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Protein Aliases: Brain protein H19; Membrane-associated protein HEM-2; MH19; NAP 1; Nck-associated protein 1; p125Nap1
Gene Aliases: C79304; H19; Hem-2; HEM2; KIAA0587; mh19; mKIAA0587; NAP1; NAP125; NCKAP1; p125Nap1