Immunogen sequence: VLIRMYNIKK TCSDPKSKPP FLLEKSMEPS LKYINKKFPN IDVRNSTQHL GPVHREKAEI IRFLTNYYQS FVD
Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 97%.
This gene encodes a member of the HEM family of tissue-specific transmembrane proteins which are highly conserved from invertebrates through mammals. This gene is only expressed in hematopoietic cells. The encoded protein is a part of the Scar/WAVE complex which plays an important role in regulating cell shape in both metazoans and plants. Alternatively spliced transcript variants encoding different isoforms have been found.[provided by RefSeq, May 2010].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Hematopoietic protein 1; Membrane-associated protein HEM-1; Nck-associated protein 1-like
Gene Aliases: HEM1; NCKAP1L
UniProt ID: (Human) P55160
Entrez Gene ID: (Human) 3071