PA5-31121 targets NDE1 in WB applications and shows reactivity with Human samples.
The PA5-31121 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 203 of Human NDE1.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
This gene encodes a member of the nuclear distribution E (NudE) family of proteins. The encoded protein is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. This protein plays an essential role in microtubule organization, mitosis and neuronal migration. Alternative splicing results in multiple transcript variants.
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Protein Aliases: HOM-TES-87; LIS1-interacting protein NUDE1; LIS1-interacting protein NUDE1, rat homolog; LIS4; Nuclear distribution protein nudE homolog 1; NUDE; nudE nuclear distribution E homolog 1; nudE nuclear distribution gene E homolog 1; NUDE1; rat homolog
Gene Aliases: HOM-TES-87; LIS4; MHAC; NDE; NDE1; NUDE; NUDE1
UniProt ID: (Human) Q9NXR1
Entrez Gene ID: (Human) 54820