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|Tested species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 186 and 369 of Human NDRG1|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-27213 targets NDRG1 in Western Blot and Immunohistochemistry (Paraffin) applications and shows reactivity with Human and mouse samples.
The PA5-27213 immunogen is recombinant fragment corresponding to a region within amino acids 186 and 369 of Human NDRG1.
This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. It is necessary for p53-mediated caspase activation and apoptosis. Mutation in this gene has been reported to be causative for hereditary motor and sensory neuropathy-Lom. Multiple alternatively spliced variants, encoding the same protein, have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
CAP43; CMT4D; Differentiation-related gene 1 protein; DRG-1; DRG1; GC4; HMSNL; N-myc downstream regulated 1; N-myc downstream-regulated gene 1 protein; NDR1; Nickel-specific induction protein Cap43; NMSL; Protein Ndr1; Protein NDRG1; protein regulated by oxygen-1; PROXY1; Reducing agents and tunicamycin-responsive protein; RIT42; RTP; TARG1; TDD5; tunicamycin-responsive protein
CAP43; CMT4D; DRG-1; DRG1; GC4; HMSNL; NDR1; NDRG1; Ndrl; NMSL; PROXY1; RIT42; RTP; TARG1; TDD5