Invitrogen

NDRG2 Polyclonal Antibody

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This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details

View all (7) NDRG2 antibodies

Datasheet

Datasheet

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NDRG2 Antibody in Immunofluorescence (IF) — Immunofluorescent staining of NDRG2 in human cell line U-251 MG shows positivity in cytoplasm, microtubule organizing center and nucleus but excluded from the nucleoli. Samples were probed using a NDRG2 Polyclonal Antibody (Product # PA5-51767).

NDRG2 Antibody in Immunohistochemistry (IHC) — Immunohistochemical staining of NDRG2 in human cerebral cortex and pancreas tissues using NDRG2 Polyclonal Antibody (Product # PA5-51767). Corresponding NDRG2 RNA-seq data are presented for the same tissues.

NDRG2 Antibody in Western Blot (WB) — Western blot analysis of NDRG2 in human liver tissue using a NDRG2 Polyclonal Antibody (Product # PA5-51767).

NDRG2 Antibody in Relative expression — Relative expression in different tissues in IHC: Detection of differential expression levels of NDRG2 demonstrates antibody specificity. Immunohistochemical analysis of NDRG2 using anti-NDRG2 Polyclonal Antibody (Product # PA5-51767), shows significant staining of NDRG2 in human cerebral cortex and shows minimal or weak staining in human pancreas tissues. The relative expression levels of NDRG2 within each tissue is shown using RNA-Seq. {RE}

Product Details

Tested Applications

Dilution

Immunocytochemistry (ICC)

1-4 µg/mL

Immunofluorescence (IF)

1-4 µg/mL

Immunohistochemistry (IHC)

1:2500-1:5000

Western Blot (WB)

0.4 µg/mL

Product Specifications

Species Reactivity

Human

Host / Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human NDRG2

Conjugate

Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

RRID

AB_2644533

Product Specific Information

Immunogen sequence: TGLTSSIPEM ILGHLFSQEE LSGNSELIQK YRNIITHAPN LDNIELYWNS YNNRRDLNFE RGGDITLRCP VMLVVGDQAP HEDAVVECNS KLDPTQTSFL KMADSGGQP

Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 94%.

Target Information

NDRG2's gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. NDRG2 is a cytoplasmic protein that may play a role in neurite outgrowth. Its gene may be involved in glioblastoma carcinogenesis.This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein that may play a role in neurite outgrowth. This gene may be involved in glioblastoma carcinogenesis. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: cytoplasmic protein Ndr1; DKFZp781G1938; FLJ25522; KIAA1248; N-myc downstream regulator 2; N-myc downstream-regulated gene 2 protein; NDR1-related protein NDR2; NDRG family member 2; Protein NDRG2; Protein Syld709613; SYLD; syld709613 protein

Gene Aliases: KIAA1248; NDRG2; SYLD

UniProt ID: (Human) Q9UN36

Entrez Gene ID: (Human) 57447

Function(s)

negative regulation of cytokine production signal transduction regulation of vascular endothelial growth factor production Wnt signaling pathway substantia nigra development cell differentiation negative regulation of smooth muscle cell proliferation negative regulation of ERK1 and ERK2 cascade regulation of platelet-derived growth factor production

Process(es)

molecular_function protein binding

NDRG2 Polyclonal Antibody

Product Details

Product Specific Information

Target Information

Bioinformatics

Material safety data sheets (MSDS)

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