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Invitrogen
NDRG2 Polyclonal Antibody
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Product Details
PA5-79722
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human NDRG2 (210-247aa NSELIQKYRNIITHAPNLDNIELYWNSYNNRRDLNFER).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: Rat Brain Tissue, Mouse Brain Tissue. IHC: mouse brain tissue, rat brain tissue.
Target Information
NDRG2's gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. NDRG2 is a cytoplasmic protein that may play a role in neurite outgrowth. Its gene may be involved in glioblastoma carcinogenesis.This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein that may play a role in neurite outgrowth. This gene may be involved in glioblastoma carcinogenesis. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Antidepressant-related protein ADRG123; cytoplasmic protein Ndr1; DKFZp781G1938; FLJ25522; N-myc downstream regulated 2; N-myc downstream regulated gene 2; N-myc downstream regulator 2; N-myc downstream-regulated gene 2 protein; NDR1-related protein NDR2; NDRG1-related protein; NDRG2var; Protein Ndr2; Protein NDRG2; Protein Syld709613; syld709613 protein
Gene Aliases: AI182517; AU040374; KIAA1248; Ndr2; NDRG2; SYLD
UniProt ID: (Human) Q9UN36, (Mouse) Q9QYG0, (Rat) Q8VBU2
Entrez Gene ID: (Human) 57447, (Mouse) 29811, (Rat) 171114
negative regulation of cytokine production
signal transduction
regulation of vascular endothelial growth factor production
Wnt signaling pathway
substantia nigra development
cell differentiation
negative regulation of smooth muscle cell proliferation
negative regulation of ERK1 and ERK2 cascade
regulation of platelet-derived growth factor production
multicellular organism development
nervous system development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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