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Immunogen sequence: TSEKSVQSFQ LKGFPFSIYG NLAVKDCCIN PHSPLIRVTK SSKLEKGSLP GTD
Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 81%.
This gene encodes a member of the heparan sulfate/heparin GlcNAc N-deacetylase/ N-sulfotransferase family. The encoded enzyme is a type II transmembrane protein that resides in the Golgi apparatus. This monomeric bifunctional enzyme catalyzes the N-deacetylation and N-sulfation of N-acetylglucosamine residues in heparan sulfate and heparin, which are the initial chemical modifications required for the biosynthesis of the functional oligosaccharide sequences that define the specific ligand binding activities of heparan sulfate and heparin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3; GlcNAc N-deacetylase/ N-sulfotransferase 3; Glucosaminyl N-deacetylase/N-sulfotransferase 3; hNDST-3; N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3; N-deacetylase/N-sulfotransferase 3; N-heparan sulfate sulfotransferase 3; N-HSST 3; NDST-3
Gene Aliases: HSST3; NDST3; UNQ2544/PRO4998
UniProt ID: (Human) O95803
Entrez Gene ID: (Human) 9348
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