Immunogen sequence: MGALVIRGIR NFNLENRAER EISKMKPSVA PRHPSTNSLL REQISLYPEV KGEIARKDEK LLSFLKDVYV DSKDPVSSLQ VKAAETCQEP KEFRLPKDHH FDMINIKSIP KGKISIVEAL TLLNNHKLFP ETWTAEKIMQ EYQLEQKDVN SLLKYFVTFE VEIFPPEDKK; Positive Samples: U-87MG, HeLa, K-562; Cellular Location: Lipid-anchor, Membrane, Mitochondrion
NADH:ubiquinone oxidoreductase (complex I) catalyzes the transfer of electrons from NADH to ubiquinone (coenzyme Q) in the first step of the mitochondrial respiratory chain, resulting in the translocation of protons across the inner mitochondrial membrane. This gene encodes a complex I assembly factor. Mutations in this gene are a cause of mitochondrial complex I deficiency.
Protein Aliases: Hormone-regulated proliferation-associated protein of 20 kDa; Hormone-regulated proliferation-associated protein of 20 kDa homolog; hormone-regulated proliferation-associated protein, 20 kDa; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 4; NADH dehydrogenase (ubiquinone) complex I, assembly factor 4; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4
Gene Aliases: 1110007M04Rik; 3000003G13Rik; AW214064; bA22L21.1; C6orf66; HRPAP20; HSPC125; My013; NDUFAF4