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Proteintech
NDUFC2 Polyclonal Antibody
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Product Details
15573-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Pig
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
NDUFC2 Fusion Protein Ag7919 (1-119 aa encoded by BC007323)
Conjugate
Form
Liquid
Concentration
0.18 mg/mL
Amount
27 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MIARRNPEP LRFLPDEARS LPPPKLTDPR LLYIGFLGYC SGLIDNLIRR RPIATAGLHR QLLYITAFFF AGYYLVKRED YLYAVRDREM FGYMKLHPED FPEEDKKTYG EIFEKFHPIR (1-119 aa encoded by BC007323)
Target Information
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 14.5b subunit of the NADH-ubiquinone dehydrogenase complex; CI-49kD; CI-B14.5b; CI-B145b; complex 1, mitochondrial respiratory chain, 49-KD subunit; complex I 49kDa subunit; complex I iron sulphur protein subunit; 49kDa subunit; complex I subunit; complex I subunit B14.5b; Complex I-49kD; Complex I-B14.5b; Complex I-B145b; HLC-1; Human lung cancer oncogene 1 protein; lung cancer oncogene 2; NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa; NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase); NADH dehydrogenase [ubiquinone] 1 subunit C2; NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial; NADH-coenzyme Q reductase; NADH-ubiquinone oxidoreductase 49 kDa subunit; NADH-ubiquinone oxidoreductase NDUFS2 subunit; NADH-ubiquinone oxidoreductase subunit B14.5b; NADHDH2; NDUFC2; unnamed protein product
Gene Aliases: 1810004I06Rik; 2010300P09Rik; AL033311; B14.5b; CI-49; CI-B14.5b; G1; HLC-1; HLC1; LHONAR2; MC1DN36; MC1DN6; NADHDH2; NDUFC2; NDUFS2; R75094
UniProt ID: (Human) O95298, (Human) O75306, (Mouse) Q9CQ54, (Mouse) Q91WD5
Entrez Gene ID: (Human) 4718, (Human) 4720, (Mouse) 68197, (Mouse) 226646
protein binding
NADH dehydrogenase (ubiquinone) activity
NADH dehydrogenase activity
electron carrier activity
oxidoreductase activity
oxidoreductase activity, acting on NAD(P)H
oxygen sensor activity
ubiquitin protein ligase binding
metal ion binding
quinone binding
NAD binding
iron-sulfur cluster binding
4 iron, 4 sulfur cluster binding
oxidoreductase
metabolite interconversion enzyme
mitochondrial electron transport, NADH to ubiquinone
aerobic respiration
positive regulation of mitochondrial membrane potential
mitochondrial respiratory chain complex I assembly
mitochondrial ATP synthesis coupled proton transport
negative regulation of NIK/NF-kappaB signaling
hydrogen ion transmembrane transport
negative regulation of reactive oxygen species biosynthetic process
positive regulation of ATP biosynthetic process
neurogenesis
gliogenesis
mitochondrial ATP synthesis coupled electron transport
neural precursor cell proliferation
cellular response to oxygen levels
transport
oxidation-reduction process
response to oxidative stress
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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