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Invitrogen
NDUFS3 Monoclonal Antibody (3F9DD2)
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FIGURE: 1 / 4
NDUFS3 Antibody (459130) in WB
Nutrients 2020 -
Figure 5 HAE activated the mitochondrial biogenesis pathway in mice livers and hearts. Con, control; P407, poloxamer 407; P407 + HAE, poloxamer 407 plus HAE at 200 mg/kg/day. ( A ) Protein levels of liver PGC-1alpha and mitochondrial complex subunits I-V (left, western blot image; right, statistical analysis). ( B ) Liver mtDNA copy number. ( C ) Liver ATP level. ( D ) Protein levels of heart PGC-1alpha and... View More
Product Details
459130
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bovine,
Human,
Mouse,
Rat
Published species
Horse,
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
3F9DD2
Immunogen
Whole mitochondria from Human Heart
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
IgG fraction
Storage buffer
HEPES buffered saline
Contains
0.02% sodium azide
Storage conditions
4°C, do not freeze
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Use Isolated mitochondria from Human, Bovine Rat and Mouse hearts; Cultured Human fibroblasts; HeLa cells; Human colon and cerebellum tissues as positive control.
Target Information
This gene encodes one of the iron-sulfur protein components of mitochondrial NADH:ubiquinone oxidoreductase. Mutations in this gene are associated with Leigh syndrome resulting from mitochondrial complex I deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CI-30kD; complex I 30kDa subunit; complex I iron sulphur protein subunit; 30 kDa subunit; Complex I-30kD; NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase); NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial; NADH dehydrogenase-ubiquinone 30 kDa subunit; NADH-ubiquinone oxidoreductase 30 kDa subunit; unnamed protein product
Gene Aliases: 0610010M09Rik; CI-30; CI-30kD; MC1DN8; NDUFS3
UniProt ID: (Bovine) P23709, (Human) O75489, (Mouse) Q9DCT2
Entrez Gene ID: (Bovine) 287327, (Human) 4722, (Mouse) 68349, (Rat) 295923
negative regulation of cell growth
oxidation-reduction process
reactive oxygen species metabolic process
negative regulation of intrinsic apoptotic signaling pathway
mitochondrial electron transport, NADH to ubiquinone
aerobic respiration
substantia nigra development
mitochondrial respiratory chain complex I assembly
mitochondrial ATP synthesis coupled proton transport
hydrogen ion transmembrane transport
transport
biological_process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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