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Proteintech
NDUFS6 Polyclonal Antibody
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Product Details
14417-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
NDUFS6 Fusion Protein Ag5762 (1-124 aa encoded by BC046155)
Conjugate
Form
Liquid
Concentration
0.16 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MAAAMTFCR LLNRCGEAAR SLPLGARCFG VRVSPTGEKV THTGQVYDDK DYRRIRFVGR QKEVNENFAI DLIAEQPVSE VETRVIACDG GGGALGHPKV YINLDKETKT GTCGYCGLQF RQHHH (1-124 aa encoded by BC046155)
Target Information
This gene encodes a subunit of the NADH:ubiquinone oxidoreductase, which is the first enzyme complex in the electron transport chain of mitochondria. This complex functions in the transfer of electrons from NADH to the respiratory chain. The subunit encoded by this gene is one of seven subunits in the iron-sulfur protein fraction. Mutations in this gene cause mitochondrial complex I deficiency, a disease that causes a wide variety of clinical disorders, including neonatal disease and adult-onset neurodegenerative disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CI-13kD-A; complex I 13kDa subunit A; complex I, mitochondrial respiratory chain, 13-kD subunit; Complex I-13kD-A; NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase); NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial; NADH dehydrogenase Fe-S protein 6; NADH ubiquinone oxidoreductase; NADH-ubiquinone oxidoreductase 13 kDa-A subunit; NADH:ubiquinone oxidoreductase NDUFS6 subunit
Gene Aliases: BC059730; CI-13kA; CI-13kD-A; CI13KDA; IP13; Ip13dis; Ndub13; NDUFS6; RATIp13dis
UniProt ID: (Human) O75380, (Mouse) P52503
Entrez Gene ID: (Human) 4726, (Mouse) 407785, (Rat) 29478
mitochondrial electron transport, NADH to ubiquinone
fatty acid metabolic process
muscle contraction
multicellular organism aging
mitochondrial respiratory chain complex I assembly
multicellular organism growth
reproductive system development
mitochondrion morphogenesis
cardiovascular system development
transport
respiratory electron transport chain
oxidation-reduction process
biological_process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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