|Immunohistochemistry (Paraffin) (IHC (P))||1:50-1:100|
|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A synthetic peptide derived from the internal region of human NDUFS6|
|Purification||Antigen affinity chromatography|
|Storage buffer||Dulbecco's PBS, pH 7.4, with 50% glycerol, 150mM NaCl|
|Contains||0.02% sodium azide|
This gene encodes a subunit of the NADH:ubiquinone oxidoreductase , which is the first enzyme complex in the electron transport chain of mitochondria. This complex functions in the transfer of electrons from NADH to the respiratory chain. The subunit encoded by this gene is one of seven subunits in the iron-sulfur protein fraction. Mutations in this gene cause mitochondrial complex I deficiency, a disease that causes a wide variety of clinical disorders, including neonatal disease and adult-onset neurodegenerative disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 13kDa (NADH-coenzyme Q reductase); CI-13kD-A; complex I 13kDa subunit A; complex I, mitochondrial respiratory chain, 13-kD subunit; Complex I-13kD-A; NADH dehydrogenase (ubiquinone) Fe-S protein 6; NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase); NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial; NADH dehydrogenase Fe-S protein 6; NADH ubiquinone oxidoreductase; NADH-ubiquinone oxidoreductase 13 kDa-A subunit; NADH:ubiquinone oxidoreductase NDUFS6 subunit; NDUFS6
Gene Aliases: BC059730; CI-13kA; CI-13kD-A; CI13KDA; IP13; Ip13dis; Ndub13; NDUFS6; RATIp13dis
Molecular Function: oxidoreductase
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