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Invitrogen
NDUFS6 Polyclonal Antibody
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Product Details
PA5-98005
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial protein (29-124AA)
Conjugate
Form
Liquid
Concentration
0.49 mg/mL
Amount
49 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
This gene encodes a subunit of the NADH:ubiquinone oxidoreductase, which is the first enzyme complex in the electron transport chain of mitochondria. This complex functions in the transfer of electrons from NADH to the respiratory chain. The subunit encoded by this gene is one of seven subunits in the iron-sulfur protein fraction. Mutations in this gene cause mitochondrial complex I deficiency, a disease that causes a wide variety of clinical disorders, including neonatal disease and adult-onset neurodegenerative disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CI-13kD-A; complex I 13kDa subunit A; complex I iron sulphur protein subunit; 13kDa subunit; complex I, mitochondrial respiratory chain, 13-kD subunit; Complex I-13kD-A; NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase); NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial; NADH dehydrogenase Fe-S protein 6; NADH-ubiquinone oxidoreductase 13 kDa-A subunit; NADH:ubiquinone oxidoreductase NDUFS6 subunit; NDUFS6; unnamed protein product
Gene Aliases: BC059730; CI-13kA; CI-13kD-A; CI13KDA; IP13; MC1DN9; NDUFS6
UniProt ID: (Human) O75380, (Mouse) P52503
Entrez Gene ID: (Human) 4726, (Mouse) 407785
kidney development
mitochondrial electron transport, NADH to ubiquinone
fatty acid metabolic process
muscle contraction
mitochondrion organization
aerobic respiration
gene expression
stem cell division
respiratory electron transport chain
DNA damage response, signal transduction by p53 class mediator
mitochondrial respiratory chain complex I assembly
multicellular organism growth
mitochondrial ATP synthesis coupled proton transport
regulation of mitochondrial membrane potential
reproductive system development
circulatory system development
mesenchymal stem cell differentiation
reactive oxygen species metabolic process
cellular senescence
mesenchymal stem cell proliferation
hydrogen ion transmembrane transport
transport
multicellular organism aging
oxidation-reduction process
mitochondrion morphogenesis
cardiovascular system development
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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