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Proteintech
NDUFS7 Polyclonal Antibody
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Product Details
15728-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
NDUFS7 Fusion Protein Ag8471 (1-213 aa encoded by BC005954)
Conjugate
Form
Liquid
Concentration
0.29 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MAVLSAPGL RGFRILGLRS SVGLAVQARG VHQSVATDGP SSTQPALPKA RAVAPKPSSR GEYVVAKLDD LVNWARRSSL WPMTFGLACC AVEMMHMAAP RYDMDRFGVV FRASPRQSDV MIVAGTLTNK MAPALRKVYD QMPEPRYVVS MGSCANGGGY YHYSYSVVRG CDRIVPVDIY IPGCPPTAEA LLYGILQLQR KIKRERRLQI WYRR (1-213 aa encoded by BC005954)
Target Information
This gene encodes a protein that is a subunit of one of the complexes that forms the mitochondrial respiratory chain. This protein is one of over 40 subunits found in complex I, the nicotinamide adenine dinucleotide (NADH):ubiquinone oxidoreductase. This complex functions in the transfer of electrons from NADH to the respiratory chain, and ubiquinone is believed to be the immediate electron acceptor for the enzyme. Mutations in this gene cause Leigh syndrome due to mitochondrial complex I deficiency, a severe neurological disorder that results in bilaterally symmetrical necrotic lesions in subcortical brain regions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CI-20kD; complex I 20kDa subunit; complex I, mitochondrial respiratory chain, 20-KD subunit; Complex I-20kD; FLJ45860; FLJ46880; MGC120002; NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase); NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial; NADH-coenzyme Q reductase; NADH-ubiquinone oxidoreductase 20 kDa subunit; NADH-ubiquinone oxidoreductase Fe-S protein 7; NADH:ubiquinone oxidoreductase PSST subunit; PSST subunit
Gene Aliases: 1010001M04Rik; CI-20; CI-20KD; MY017; NDUFS7; PSST
UniProt ID: (Human) O75251, (Mouse) Q9DC70
Entrez Gene ID: (Human) 374291, (Mouse) 75406, (Rat) 362837
protease binding
NADH dehydrogenase activity
protein binding
NADH dehydrogenase (ubiquinone) activity
oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
metal ion binding
quinone binding
4 iron, 4 sulfur cluster binding
oxidoreductase activity
iron-sulfur cluster binding
dehydrogenase
oxidoreductase
metabolite interconversion enzyme
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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