Positive Control: mouse heart
Predicted Reactivity: Human (100%), Rat (93%), Bovine (93%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
Nebulette encodes a nebulin like protein that is abundantly expressed in cardiac muscle. The encoded protein binds actin and interacts with thin filaments and Z-line associated proteins in striated muscle. This protein may be involved in cardiac myofibril assembly. A shorter isoform of this protein termed LIM nebulette is expressed in non-muscle cells and may function as a component of focal adhesion complexes. Alternate splicing results in multiple transcript variants.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Actin-binding Z-disk protein; LASP2; LIM and SH3 protein 2; LIM zinc-binding domain-containing Nebulette; LIM-nebulette; LNEBL; NEBL; Nebulette
Gene Aliases: 1200007O21Rik; A630080F05Rik; BB140644; D830029A09Rik; LASP2; LNEBL; NEBL