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NEK1 Polyclonal Antibody
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Product Details
BS-7814R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human NEK1, amino acids 301-400.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
NEK1 is a serine/threonine protein kinase, related to the NIMA cell cycle regulator, and is highly expressed in meiotic germ cells. The kinase may function early in the DNA damage response pathway. NEK1 may also participate in polycystic kidney disease and neural cell development. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZp686D06121; DKFZp686K12169; kidney, anemia and testis; MGC138800; Nek1 serine/threonine- and tyrosine-specific protein kinase; Never in mitosis A-related kinase 1; NIMA (never in mitosis gene a)-related expressed kinase 1; NIMA (never in mitosis gene a)-related kinase 1; NIMA-related kinase 1; NimA-related protein kinase 1; NY REN55; NY-REN-55 antigen; protein-serine/threonine kinase; Renal carcinoma antigen NY-REN-55; Serine/threonine-protein kinase Nek1; unnamed protein product
Gene Aliases: ALS24; D8Ertd790e; kat; KIAA1901; NEK1; NY-REN-55; OFD2; SRPS2; SRPS2A; SRTD6
UniProt ID: (Human) Q96PY6, (Mouse) P51954
Entrez Gene ID: (Human) 4750, (Rat) 290705, (Mouse) 18004
nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
protein tyrosine kinase activity
protein binding
ATP binding
kinase activity
transferase activity
metal ion binding
14-3-3 protein binding
protein serine kinase activity
MAP kinase kinase activity
transferase activity, transferring phosphorus-containing groups
non-receptor serine/threonine protein kinase
protein phosphorylation
cell projection organization
cell division
cilium morphogenesis
MAPK cascade
activation of MAPK activity
kidney development
cellular response to DNA damage stimulus
spermatogenesis
response to ionizing radiation
multicellular organism growth
cilium assembly
cell cycle
mitotic nuclear division
phosphorylation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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