Immunogen sequence: DFGVSRLLMG SCDLATTLTG TPHYMSPEAL KHQGYDTKSD IWSLACILYE MCCMNHAFAG SNFLSIVLKI VEGDTPSLPE RYPKELNAIM ESMLNKNPSL RPSAIEILKI PYLDEQLQNL MC
Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 82%.
This gene encodes a member of the never in mitosis gene A family of kinases. The encoded protein localizes to the nucleoli, and may function with NEK2A in the S-phase checkpoint. The encoded protein appears to play roles in DNA replication and response to genotoxic stress. Alternatively spliced transcript variants have been described.
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Protein Aliases: Never in mitosis A-related kinase 11; NIMA (never in mitosis gene a)- related kinase 11; NimA-related protein kinase 11; Serine/threonine-protein kinase Nek11
Gene Aliases: NEK11
UniProt ID: (Human) Q8NG66
Entrez Gene ID: (Human) 79858
Molecular Function: non-receptor serine/threonine protein kinase